Fig 1: Synovial fluid S100A8, S100A9 and α-defensin were detected by MALDI-TOF-MS in PJI and non-PJI groups. PJI – periprosthetic joint infection; m/z=3374, HNP1; m/z=3345, HNP2; m/z=3489, HNP3; m/z=10833, S100A8; m/z=12688, des-MTCKM S100A9; m/z=13151, des-M S100A9; m/z=13273, S-nitrosylated S100A9; m/z=12249; IFS – internal reference standards. This figure was generated using QuanPRO protein quantitation mass spectrometer, Intelligene Biosystems (Qingdao) Co., Ltd., Beijing, China.
Fig 2: Scatterplot analysis of synovial fluid S100A8, S100A9, HNP1-3 levels in PJI and non-PJI groups. (A) Scatterplot analysis of synovial fluid S100A8 levels in PJI and non-PJI groups. (B) Scatterplot analysis of synovial fluid S100A9 levels in PJI and non-PJI groups. (C) Scatterplot analysis of synovial fluid HNP1-3 levels in PJI and non-PJI groups. PJI – periprosthetic joint infection. * Significance difference between the groups, P<0.001. This figure was generated using GraphPad Prism 8.3.0, GraphPad Software Company, USA.
Fig 3: ROC analysis of common infection biomarkers for the diagnosis of periprosthetic joint infection. S100A8 – S100 calcium-binding protein A8; S100A9 – S100 calcium-binding protein A9; HNP – human neutrophil peptides; SF-WBC – synovial fluid white blood cells count; SF-PMN – percentage of polymorphonuclear neutrophil in the synovial fluid; ESR – erythrocyte sedimentation rate; WBC – whole blood white blood cell count; CRP – whole blood C-reactive protein; IL-6 – plasma interleukin-6; D-D – plasma D-dimer; Fib – plasma fibrinogen. This figure was generated using GraphPad Prism 8.3.0, Graphpad Software Company, USA.
Supplier Page from Sino Biological, Inc. for Human S100A8 / CAGA / p8 Protein (His Tag)